BSA-Based Dose Calculator (mg/m²)
Calculates patient Body Surface Area (Mosteller m²) and required drug dose (mg) for mg/m² regimens.
⚠️ Educational Calculation & Clinical Safety Safeguard: High-alert chemotherapy and immunosuppressant BSA doses require independent double-check by two pharmacists. Educational calculations do not replace clinician assessment, patient-specific laboratory monitoring, or institutional prescribing protocols.
Interactive Calculator
Allowed physiological/compounding range: 30 to 250 cm
Allowed physiological/compounding range: 1 to 300 kg
Allowed physiological/compounding range: 0.1 to 5000 mg/m²
Calculated Output (mg (with BSA in m²))
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Step-by-Step Mathematical Derivation & Explanation:
Validated Formula & Conversion Rules
BSA (m²) = √([Height(cm) × Weight(kg)] / 3600); Total Dose (mg) = BSA (m²) × Dose (mg/m²)Worked Clinical Example
Height 170 cm, Weight 68 kg: BSA = √(11560 / 3600) = √3.2111 = 1.792 m². At 100 mg/m², Total Dose = 179.2 mg.
Rounding Rules, Clinical Interpretation, Assumptions & Known Limitations
- 1. Purpose: Calculates patient Body Surface Area (Mosteller m²) and required drug dose (mg) for mg/m² regimens.
- 2. Required Inputs & Validated Units: Patient Height (cm, range 30–250), Patient Weight (kg, range 1–300), Prescribed Dose per m² (mg/m², range 0.1–5000)
- 3. Output Unit:
mg (with BSA in m²) - 4. Result Interpretation Notes: Used primarily for oncology, paediatric, and narrow-therapeutic-index regimens dosed per m² of Body Surface Area.
- 5. Rounding Guidance: Round BSA to 2 decimal places (m²) and cytotoxic/specialty doses per institutional protocol.
- 6. Mathematical & Clinical Assumptions: Uses the Mosteller square-root equation √([Height(cm) × Weight(kg)] / 3600).
- 7. Known Limitations & Contraindications to Formula Use: In cachexia, severe oedema, or ascites, BSA may overestimate extravascular distribution volume; verify protocol-specific BSA capping rules (e.g., 2.0 m² cap).
- 8. Supporting Compendial & Clinical References: Indian Pharmacopoeia (IP 2022), National Formulary of India (NFI), British National Formulary (BNF), and NCBI Bookshelf Clinical Pharmacology Compendia.